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KMID : 0365819650050010077
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Journal of Pusan Medical College
1965 Volume.5 No. 1 p.77 ~ p.83
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Two Cases of Multiple Myelonia
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Abstract
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The multiple myeloma, once considered an extremely rare disease, has recently been reported with relatively increasing frequency. Whether this has been due to an actual increased incidence of the disease or to advanced diagnostic methods is not known. This disorder is a malignant neoplasm which arises in the bone marrow primarily and develops proliferation of atypical plasma cells with an abnormal picture
of the plasma proteins `and may thus involve th3 entire skeletal system of the holy. Finally this takes the down hill course to death. The etiology of this disorder is still uncertain.
Recently authors have experienced two cases of this disease and the cases are reported in this paper with a review of the literature. The first case; 59 years old, male, observed at the Pusan National University Hospital in 1963 with the picture of the normal plasma protein pattern by the blood chemical study and by the electro-phoretic analysis. However the Bence-Jones protein ´in the urine was present. Ia the bone marrow, the atypical plasma cell proliferation was noticed. The X-ray findings of the bones revealed the typical picture of this disease.
The second case: 42 year old, male, observed on the above same time and at the same place. The study of the blood chemical examination showed the hyperprotenemia accompanied by the elevated globulin. In the paper electrophoresis, the case was one of the myeloma of the globulin pattern. However no Bence Jones protein was found in the urine.
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